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HIV, Pharyngitis, and Disseminated Rash  



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BACKGROUND
A 61-year-old woman with HIV infection and a CD4+ T-lymphocyte count of 280 cells per cubic millimeter presents with a fever, pharyngitis, and dysphagia that have lasted 3 days. Her physical examination is remarkable for an ulcerative lesion with exudates in the left tonsillar fossa. She has no drooling or stridor. The remaining physical findings are notable for generalized lymphadenopathy; somnolence with arousability; and a generalized rash with macules, papules, pustules, and vesicles, which primarily appear on the face, trunk, and abdomen but not palms or soles. A CT scan of the neck is obtained to evaluate for a retropharyngeal abscess. The CT scan reveals an abnormal, asymmetric, soft tissue thickening at the floor of the mouth and at the base of the tongue, with epiglottic swelling and inflammation extending into the soft tissues of the neck. The parotid gland is not involved. The white blood cell count and blood chemistry findings are normal.
Hint
See the stain of a skin lesion.
Author: Marilyn G. Foreman, MD, David Oruma, MD, Sajiv Gugneja, MD, and H. Gene Stringer, MD
Morehouse School of Medicine
eMedicine Editor: John Leung, MD
Northwestern University, Northwestern Memorial Hospital
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