Scientific Session... October 16, 2000

9.20 a.m.

WELCOME V. Silingardi, U. Torelli

9.30 a.m.

INTRODUCTION S. Sacchi

9.40 a.m.

BIOLOGICAL OVERVIEW Chairmen: G. Pizzolo, B. Falini
-Myeloid- and B-antigens as a target of immunotherapy. L. Baldini
-Rituximab mechanisms of action. M. Introna
-Clinical pharmacokinetic of Rituximab. M. Regazzi
-Radiolabeled monoclonal antibody: mechanisms of action. M.S. Kaminski
-CD33 antibody mediated chemotherapy: Laboratory studies on the in vivo effectivness of CMA-676. J.J.M. Van Dongen

11.40 a.m.

Coffe Break

12.00 a.m.

-CD30 molecule as a target antigen for immunotherapy. B. Falini
Panel discussion
chaired by G. Pizzolo and B. Falini:
Issues and new approaches with conjugate and unconjugate monoclonal antibodies

1.00 p.m.

Lunch

2.15 p.m.

MONOCLONAL ANTIBODY THERAPY I
Malignant lymphoma. Chairmen: A. Pileri, S. Tura
-Rituximab in combination with chemotherapy. P.L. Zinzani
-
Rituximab in combination with biological response modifiers. S. Sacchi
-Radioimmunotherapy with I131-labeled anti CD20 monoclonal antibody. M.S. Kaminski
-
Radioimmunotherapy with Y90-labeled anti CD20 monoclonal antibody. L.I. Gordon

4.15 p.m.

Coffe Break

4.30 p.m.

-Rituximab in the treatment of mantle-cell lymphoma. J.M. Foran
-High dose chemotherapy and in-vivo purging with Rituximab. C. Tarella
-The true relevance of molecular remission in follicular lymphoma. G. Saglio

6.00 p.m.

Panel discussion chaired by M. Brugiatelli and G.L. Castoldi:
Monoclonal antibodies therapy in NHL: is the future here?